If you mean by downloading the client itself, no. You can change the area in which you want to be on (NA, EUWest,EUNE, etc.) before you hit "Launch".
You have to be on the exact server they are on to play with that person though (or transfer, but that costs 2,600 rp or something like that). I play on NA and transferred one of my lvl 30 accounts to EUNE to play with Marcin
. Doing so, your NA friends list will not be transferred over with said account due to being on separate servers, and it will effect your ping.